Grey's Anatomy losing two major female leads

Two stars have been unexpectedly cut from the series. Photo credit: Grey's Anatomy

Warning: Grey's Anatomy spoilers ahead.

Another one bites the dust. 

In a shocking announcement, two fan favourite, long-time cast members of Grey's Anatomy are leaving the show at the end of the current season.

Deadline reports Jessica Capshaw and Sarah Drew are being let go from the hit medical drama at the end of season 14 for "creative reasons".

Capshaw has played Dr Arizona Robbins for a decade, while Drew - aka Dr April Kepner - has been on the show for nine years.

Both stars took to social media to express their opinions on the news. From the sounds of it, neither was expecting to be let go.

According to Drew, she found out she would not be returning for season 15 less than two days ago.

Series creator Shonda Rhimes said in a statement: "It's always hard for me to say goodbye to any of my characters... I will be forever grateful to both Jessica and Sarah for bringing these characters to life with such vibrant performances and for inspiring women around the globe. They will always be a part of our Shondaland family."

It is unknown how the two characters will be written out of the show.