A passenger train has collided with a freight train in the US state of South Carolina, killing at least two people and injuring at least 116.
The Amtrak train with 139 passengers and eight crew members aboard was travelling between New York and Miami when it collided with the CSX freight train and derailed, Amtrak said in a statement on its website on Sunday (local time).
"Amtrak Train 91, operating between New York and Miami, came in contact with a CSX freight train at around 2.35am in Cayce, South Carolina," the Amtrak statement said.
"The lead engine was derailed, as well as some passenger cars."
The train was part of Amtrak' Silver Star Service and was headed for Miami, local media reported.
"The injuries range from cuts and bruises to severe broken bones. All the injured have been transported to local hospitals," said South Carolina Emergency Management Division public information officer Derrec Becker.
The Lexington County Sheriff's Department said on its website that a shelter for passengers was set up at a nearby middle school and that everyone was off the train and the Red Cross was assisting them.