James Corden's Carpool Karaoke sessions are famously full of laughs, but there's one that he says is so touching it made him cry.
Called "50 mums, 50 kids and one extra chromosome", the video was made by a group of mothers with children who have Down syndrome.
The mums and kids can be seen lip-syncing and performing "Makaton" to the tune of Christina Perri's 'A Thousand Years'.
Makaton is a language programme that uses signs and symbols as well as speech. It was designed to be used by those with learning or communication difficulties.
The mothers who appear in the video are all part of a Facebook group called "Designer Genes" for parents of children with Down syndrome. They decided to create the fun clip ahead of World Down Syndrome Day on March 21 to celebrate their kids.
Since being published a week ago, the video now has more than 500,000 YouTube views. It even caught the attention of British comedian Corden, the original creator of the Carpool Karaoke phenomenon.
Singer Perri also tweeted her support of the video, which uses her 2011 hit song.
Many parents of children with Down's syndrome also took to social media to share how meaningful the video was to them.