Roseanne could be returning for a second reboot - without Roseanne Barr

The series ended, rebooted and was cut again, but it seems Roseanne just won't let go.

TMZ reports the sitcom, embroiled in controversy, could be in for its second reboot - this time focused around supporting character Darlene.

ABC cancelled the show after lead actress Roseanne Barr tweeted that Obama aide Valerie Jarrett - an African-American woman - looked like the offspring of the Muslim Brotherhood and Planet of the Apes.

But now Sara Gilbert, who plays Darlene, has reportedly approached other characters in the sitcom gauging their interest in continuing without Barr, TMZ reports.

Sources tell TMZ ABC is "very interested", as they attempt to salvage the jobs of those cast and crew affected by Barr's outburst.

Barr apologised for the racist tweet she posted, deleted it and announced she would be leaving Twitter. However she then went on to fight back with those who called her out online.

Gilbert responded to Barr's remarks on Twitter calling them "abhorrent" - a response Barr then described as "unreal".

Co-actor Michael Fishman, who also criticised Barr, has too been on the receiving end of an angry tweet.

"You throw me under the bus. nice!" Barr said.

Barr went on to blame Ambien, an insomnia drug, for her "egregious indefensible" mistake.

"It was 2 in the morning and I was ambien tweeting," she wrote in a tweet she later deleted.

Sanofi, the company which makes the hypnotic sleep aid, wasn't impressed.

"While all pharmaceutical treatments have side effects, racism is not a known side effect of any Sanofi medication," it said.

Newshub.