Gucci's new line was presented on Tuesday night in Rome - and the garments carried a message other than fashion.
A jacket emblazoned with "My body my choice," a t-shirt with "Chime for change" (Gucci's gender equality campaign) and a gown embroidered with the female reproductive system were all walked down the runway.
Other pieces carried the date "May 22 1978" - the day the Italian law for social protection of motherhood and abortion came into effect.
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"It's unbelievable that around the world there are still people who believe that they can control a woman's body, a woman's choice. I will always stand behind the freedom of being, always," Gucci's creative director Alessandro Michele told Independent.
The politically charged collection follows a slew of law changes across eight states in America which limit access to abortions.
Georgia became the fourth state to legalise a "heartbeat bill" which makes abortion illegal after a heartbeat is detected. Kentucky, Missisippi and Ohio have also approved this ban.
Alabama has outlawed abortion completely, even for cases of rape or incest. Any doctor who carries out the procedure could face a felony conviction and a life sentence.
A number of celebrities have spoken out in protest of the laws, including Alyssa Milano and Lady Gaga.