Wales flyhalf Gareth Anscombe has been ruled out of Rugby World Cup contention, after suffering a knee injury during his team's loss to England in a warm-up match.
New Zealand-born Anscombe, 28, suffered an anterior cruciate ligament injury in the first half on Sunday and tried to play through the pain, before leaving the field.
"Gareth Anscombe is out of Rugby World Cup contention, after sustaining an anterior cruciate ligament injury in the match against England yesterday," the WRU confirmed.
"His prognosis and management will be determined following further specialist reviews.
"The Wales squad and management would like to wish Gareth the very best with his recovery."
Anscombe had established himself as first-choice Wales flyhalf this year.
Coach Warren Gatland will name his 31-man World Cup squad in early September, with Dan Biggar, Jarrod Evans and Rhys Patchell in contention for the number 10 jersey.
Wales play England again in another warm-up match in Cardiff on Saturday, before facing Ireland at home and away.
They begin their World Cup Pool D campaign on September 23 against Georgia in Toyota City.
Join us at 7:30pm Saturday for live updates of the All Blacks v Wallabies Bledislie Cop clash