PSV came from behind to beat Manchester United 2-1 in a match that will be overshadowed by a horrific injury to Luke Shaw.
The Champions League group stage tie was stopped for nine minutes while the Man United defender was treated for a serious leg injury after landing awkwardly in a tackle.
WATCH MORE: Shaw breaks leg in PSV loss
Memphis Depay, who joined United from PSV in the transfer window, scored the opening goal with an individual piece of brilliance.
The quick-footed Depay beat two defenders before slotting the ball through the legs of goalkeeper Jeroen Zoet.
United continued to make chances, but it was PSV who managed to find a goal before halftime when Hector Moreno's header took a wicked deflection off United's Daley Blind.
A swift counter attack gave PSV the lead when Luciano Narsingh headed in a Maxime Lestienne cross.
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