Leonardo Ulloa scored a late winner against Norwich as Leicester solidified their spot at the top of the Premier League table, moving five points clear of second-placed Tottenham.
The Argentine was on hand to finish off a Marc Albrighton cross and claim a 1-0 win for the Foxes, who look set to take their unprecedented title push right to the wire.
Norwich, meanwhile, are only outside of the relegation zone on goal difference -- and with Newcastle still to play this weekend, they could fall into it by the end of the round.
The away side looked the better of the two teams for a good portion of the game, with Leicester failing to display the kind of quality they have exhibited all season.
Norwich forwards Cameron Jerome and Nathan Redmond wasted one good chance apiece in search of a victory, but Ulloa's timely goal handed the Foxes victory.
At St Mary's Stadium, Southampton went ahead against Chelsea with a Shane Long strike right before halftime, before a pair of goals in the final 20 minutes secured victory for the Blues.
Cesc Fabregas scored the first, his cross-come-shot fooling Saints' keeper Fraser Forster and creeping into the far corner, before Branislav Ivanovic got his head to a Willian corner.
Chelsea continue to make their way up the table after a disastrous start to their title defence, rising to 11th after the win.
However Aston Villa's own terrible season was prolonged further by Stoke City, two Marko Arnautovic goals proving the difference for the home side.
The first was a penalty after Phil Bardsley was brought down by Ashley Westwood in the 51st minute, before the Austrian playmaker doubled his tally when he chested in eight minutes later.
West Ham continued their splendid campaign with a 1-0 win over Sunderland, Michail Antonio striking low past Vito Mannone at the half-hour mark.
Leandro Bacuna gave the Villans some hope for a late equaliser, but the West Midlands side failed to create any more clear-cut opportunities.
Watford and Bournemouth played out a drab draw at Vicarage Road -- Odion Ighalo missing two close-range chances for the Hornets, while the Cherries' best opportunity was a looping shot from Max Gradel.
In the morning's late fixture, West Bromwich Albion nearly gave up a 3-0 lead before finally downing Crystal Palace at the Hawthorns.
Craig Gardner got the hosts off to a flyer, running onto a parried Salomon Rondon shot to tap home, before Craig Dawson compounded Palace's misery with a dominant header from a free-kick.
Within half-an-hour young striker Saido Berahino had made it three for the home side, volleying home wonderfully from a Stephane Sessegnon through-ball.
However Palace were not out of the match, and just three minutes into the second half Connor Wickham pounced on some uncertain defending from Jonas Olsson to prod beyond Albion goalkeeper Ben Foster.
The Englishman then notched his second of the match, sending a destructive volley into the net from a free-kick -- but that was to be all the game's drama as West Brom ran out victors.
Manchester United and Arsenal play in the game of the round tomorrow morning, with Tottenham hosting Swansea at White Hart Lane.
Liverpool and Manchester City also play tomorrow, thought their game is at Wembley Stadium in the League Cup final.
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