Chelsea ended Manchester City's unbeaten Premier League run with a 2-0 win at Stamford Bridge – a result that leaves Liverpool top of the standings after their 4-0 win over Bournemouth.
Forward Mohamed Salah scored three goals against the Cherries, leaving Liverpool one point ahead of City, who were undone by goals from N'Golo Kante and David Luiz at Stamford Bridge.
Liverpool manager Juergen Klopp says Liverpool are happy to be on top but are focused only on themselves.
"We are not really interested in other teams," he said.
"We only have three days until Napoli [in the Champions League], which is a big one. It is Bournemouth celebrating day. Let's go home, have food and go again."
Criticised in some quarters for his form in recent weeks, Salah was back to his best as Liverpool matched their 4-0 win at Bournemouth from last season.
The first goal had a touch of fortune about it as Salah followed up Roberto Firmino's dipping shot to fire in the rebound, though TV replays suggested he was marginally offside.
There was no controversy about the second, though, as he shrugged off a foul to slip the ball into the corner, three minutes into the second half.
Steve Cook turned in Andy Robertson's cross to make it 3-0 on 68 minutes and Salah then added his third, twice rounding the goalkeeper before poking the ball home.
Liverpool are now the only unbeaten team in the league after City were beaten at Chelsea.
City dominated possession and had more shots but were beaten by Chelsea's first shot, through Kante on the stroke of half-time.
Beaten by Wolves last time out, Chelsea were a different team altogether and from their first corner, on 78 minutes, Luiz headed home the second goal.
Third-placed Tottenham moved to within six points of top spot - and remained two points ahead of fourth-placed Chelsea - thanks to a 2-0 win at Leicester.
Arsenal needed a stunning bicycle kick by Lucas Torreira after 83 minutes to seal the win against Aaron Mooy's valiant Huddersfield team.
Manchester United shrugged off a poor recent run as they beat bottom side Fulham 4-1, Ashley Young, Juan Mata, Romelu Lukaku and Marcus Rashford scoring the goals.
Chris Wood's Burnley moved out of the bottom three after a 1-0 victory over Brighton.
Cardiff edged further from danger with their own 1-0 win over struggling Southampton in Ralph Hasenhuettl's first game in charge of the Saints while West Ham beat Crystal Palace 3-2.