Premier League sides Fulham and Leicester City have been knocked out of the FA Cup, losing to fourth-division sides Oldham Athletic and Newport County 2-1 in the third round on Monday (NZ time).
Fulham and Leicester join Cardiff City, who lost to Gillingham 1-0 on Sunday, as the Premier League teams to suffer early exits in the contest for the oldest prize in English football.
Premier League sides come into play in the third round proper (round of 64), with lower league teams battling it out in the early stages of the competition.
Oldham had to come from a goal down in the final 14 minutes to beat Fulham at Craven Cottage.
Defender Denis Odoi gave Fulham the lead shortly after halftime, before loan striker Sam Surridge levelled from the spot in the 76th minute.
Substitute striker Aleksandar Mitrovic then missed a penalty kick, before Oldham's Callum Lang headed in the winner in the 88th minute.
"It is one you have to savour," Oldham boss Pete Wild said. "I am the most proud man in Oldham, I can't believe it."
Newport County also needed a late goal to beat 2016 Premier League champions Leicester in south Wales.
Padraig Amond's 85th-minute penalty fired the Welsh side into the fourth round as 2-1 winners, after Mark Albrighton was guilty of a needless handball in the area.
The penalty came just three minutes after Rachid Ghezzal had levelled for the Foxes, who had trailed for most of the match, after Jamille Matt put Newport in the lead after 10 minutes.
Leicester finished with 70 percent possession and took 24 shots, compared to Newport's nine, but could only find the back of the net once.
"I'm so proud of the players," Newport manager Michael Fylnn told BBC Wales.
"They were excellent from start to finish - the amount of work they did off the ball and the chances we created as well."
The other big upset of the day occurred when non-league Barnet beat Sheffield United 1-0.
Striker Shaquile Coulthirst scored a 21st-minute penalty to send Barnet through to the fourth round, where they'll be the only non-league team to feature in the round of 32.
Premier League champions Manchester City and Watford had no such problems, claiming 7-0 and 2-0 wins over Rotherham and Woking respectively.
City fielded a strong team, as manager Pep Guardiola chased his first FA Cup - the only domestic cup the Spaniard hasn't won while coaching Manchester.
Raheem Sterling, Phil Foden and Semi Ajayi all scored in the first half, while Gabriel Jesus, Riyad Mahrez, Nicolas Otamendi and Leroy Sane completed the rout with second-half goals.
Championship leaders Leeds United went down 2-1 at Queens Park Rangers, while Millwall and Doncaster Rovers both recorded 2-1 and 3-1 wins over Hull and Preston North End.