President Donald Trump, addressing the deadliest mass shooting in US history, said that the gun attack in Las Vegas was an act of "pure evil".
"We are joined together in sadness, shock and grief," Mr Trump said from the Diplomatic Room at the White House.
Mr Trump called for unity in the wake of the attack, and said that he would visit Las Vegas on Wednesday.
"In moments of tragedy and horror, America comes together as one," Mr Trump said.
He did not go into the details of the shooting or the assailant's motives, nor did he address the politics surrounding gun violence.
Rather, he quoted scripture and delivered a message of solace.
"Our unity cannot be shattered by evil, our bonds cannot be broken by violence, and though we feel such great anger at the senseless murder of our fellow citizens, it is our love that defines us today," Mr Trump said.
At least 58 people were dead and more than 500 injured when a shooter opened fire from the 32nd floor of a hotel on the Las Vegas strip down on an outdoor concert late on Sunday night.
Police identified the gunman as Stephen Paddock, 64, of Mesquite, Nevada, and believe that he killed himself before they got to his room at the Mandalay Bay Hotel.
Earlier on Monday, the Department of Homeland Security said that "at this time, we have no information to indicate a specific credible threat involving other public venues in the country.
However, increased security in and around public places and events may be experienced as officials take additional precautions."
Trump also ordered all flags to be placed at half staff.
Trump also is scheduled to visit Puerto Rico on Tuesday in the wake of ongoing recovery efforts following Hurricane Maria.