Gaza's Health Ministry said Israeli fire killed two Palestinians at protests along the Gaza border on Friday.
It said the two men succumbed to wounds sustained earlier in the day. It said a total of 525 people have been wounded at the protest over the course of the day, 92 of them by live fire.
Witnesses said one of the men was shot close to the fence where he was throwing stones at soldiers.
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Israel says it's defending its sovereign border, including nearby communities, and accuses Hamas of trying to carry out attacks under the guise of the mass protests.
Israel's use of potentially lethal force against the protesters has drawn international criticism.
At least 115 Palestinian protesters, the vast majority unarmed, have been killed and close to 3,800 have been wounded by Israeli army fire since the marches began in late March.