A tornado has pulverised buildings around Dayton, Ohio, injuring at least 35 people and requiring emergency officials to send out snow ploughs to clear debris from a major highway.
At least two other tornadoes have touched down near the city, including one near Wright-Patterson Air Force Base, just east of the city, media reports said.
At least 35 people in and around Dayton went to hospitals with injuries, most of them minor, according to Kettering Health Network spokeswoman Elizabeth Long.
"We've had injuries ranging from lacerations to bumps and bruises from folks being thrown around in their houses due to the storms," she said.
There have been no reports of fatalities.
"We had a great warning system in the area," Long said.
The latest storm follows tornadoes and floods that have killed at least six people in Oklahoma during the previous week, including two people in El Reno on Saturday.
More than 60,000 homes and businesses in Ohio were left without power on Monday morning, according to the PowerOutage.
Twitter users posted images of debris flying in the air and damaged mobile homes and cars.
Media images online showed snow ploughs from the Ohio Department of Transportation clearing debris from US Interstate 75, just north of the city.