Hannah Tamaki is running for the Waiariki seat in the 2020 election, Vision New Zealand announced on Wednesday.
Tamaki, the party's leader, is promising "new and innovative solutions for Māori" if successful.
She will be releasing the outline for the party's new First Peoples Policy on Thursday.
The policy will "set the landscape" for Māori's economic future, "lifting thousands out of social dependence to self-dependency", according to a statement released by Vision NZ.
"Labour has had its turn, the Māori Party has had its turn, now it’s my turn," Tamaki, the wife of Destiny Church founder Brian Tamaki, said in the statement.
"There is a new breed of politician on the rise, one who keeps their promises and who leads a party with totally new and innovative solutions for Māori.
"I am determined to work with others in Waiariki to cease homelessness, child uplifts, broken homes, and inequality, because it’s time to get to the root of the problem and heal our homes."
Tamaki's candidacy for the seat follows a period of controversy for Destiny Church amid New Zealand's COVID-19 outbreak, with Tamaki's husband publicly pushing back against the stringent restrictions.
In May, the self-proclaimed apostle was adamant a Destiny Church service would run despite the cap on religious and social gatherings under alert level 2. He also accused Prime Minister Jacinda Ardern of duping the public with "her deception and front" and preventing New Zealanders' "freedom to worship".
In March, Brian Tamaki declared that Destiny Church is not afraid of COVID-19 and would remain open amid the outbreak, claiming the churches fulfil a need for "faith, hope and the presence of God" during a time of fear.
In the past, Vision NZ has come under fire for promising to ban "mosques, temples and other foreign buildings", with Tamaki calling for immigration to be cut by 97 percent last year.