Kurdish militants have attacked a police station in southeast Turkey with a truck bomb, killing six people including a baby and two toddlers.
It was one of the biggest strikes since the conflict reignited in July, security officials said.
The overnight blast ripped the facade off the station in the small town of Cinar. A Reuters reporter saw nearby windows blown out, shop shutters mangled and streets covered in debris.
The mainly Kurdish region has suffered a surge in violence since a two-year ceasefire between the state and Kurdistan Workers' Party (PKK) rebels collapsed, reviving an insurgency that has killed 40,000 people over three decades.
The conflict is a challenge to Turkey's security forces, which are fighting on two fronts. On Tuesday, 10 German tourists were killed in Istanbul in a suicide attack by a suspected Islamic State militant.
Prime Minister Ahmet Davutoglu said a five-month-old baby was among the dead in Cinar, vowing in a speech that Turkey would continue its fight against "every kind of terror".
Security sources said a one-year-old and a five-year-old had also died, along with a police officer and an unnamed fifth person, and 39 people were wounded, including six police.
PKK militants attacked the police station and adjoining accommodation at around 11.30pm local time, the provincial governor's office said in a statement.
There was no immediate claim of responsibility. As rescue workers continued to search for bodies, the Reuters reporter saw a sixth body being pulled from the wreckage. A security source said it was that of a policeman's wife.
A security source said 1.5 tonnes of explosives were used in the blast.
Coinciding with the bomb attack, PKK fighters opened fire on a nearby security complex, triggering a firefight, but no casualties were reported, the statement said.
The PKK, designated a terrorist group by Turkey, the United States and the European Union, says it is fighting for autonomy and greater rights for Turkey's Kurds.